1-(4-Nitrophenyl)ethanol(CAS: 6531-13-1)

1-(4-Nitrophenyl)ethanol (CAS: 6531-13-1) is a colorless liquid with a molecular weight of 190.13 g/mol. It has a pKa of approximately 9.5 and a boiling point of 220°C. The compound is slightly soluble in water but miscible with common organic solvents. It is mildly reactive towards bases and oxidizing agents.

1-(4-Nitrophenyl)ethanol is typically synthesized by the nitration of 1-phenylethanol followed by hydrolysis. This involves treating 1-phenylethanol with a mixture of concentrated sulfuric acid and nitric acid under controlled temperature conditions. The nitration step requires careful monitoring to achieve the desired yield and selectivity.

1-(4-Nitrophenyl)ethanol (CAS: 6531-13-1) is used in the pharmaceutical industry for the synthesis of certain drug molecules. It is also utilized in the chemical industry for the production of dyes and pigments. Additionally, it serves as a reagent in polymer chemistry and as a precursor in the development of sensors and semiconductors.

When handling 1-(4-Nitrophenyl)ethanol (CAS: 6531-13-1), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood. In case of a spill, immediately clean up with appropriate absorbent materials and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for more detailed handling instructions.