N-Benzyl-4-bromobenzamide(CAS: 80311-89-3)

N-Benzyl-4-bromobenzamide (CAS: 80311-89-3) is a crystalline solid with a molecular weight of approximately 271.04 g/mol. It has a low solubility in water but is soluble in common organic solvents like methanol and acetone. The compound is moderately reactive with nucleophiles and electrophiles, making it suitable for various chemical transformations. Its melting point is around 125-127°C.

N-Benzyl-4-bromobenzamide (CAS: 80311-89-3) is commonly synthesized through the reaction of 4-bromobenzoic acid with benzylamine in the presence of a coupling agent like 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and 4-(4-N-morpholino)pentane-1-sulfonic acid (MOPSO). The yield is typically around 85%, and the product is isolated by recrystallization from an appropriate solvent.

N-Benzyl-4-bromobenzamide (CAS: 80311-89-3) is used in the pharmaceutical industry for the synthesis of various medicinal compounds. It also finds applications in the polymer industry as a stabilizer and in sensors for its ability to interact with specific analytes. Additionally, it is used in the semiconductor industry for the fabrication of thin films and as a precursor in chemical vapor deposition processes.

When handling N-Benzyl-4-bromobenzamide (CAS: 80311-89-3), it is essential to use personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be performed in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.