(2E)-3-(4-Methoxyphenyl)acrylic acid(CAS: 943-89-5)

(2E)-3-(4-Methoxyphenyl)acrylic acid is a colorless solid with a molecular weight of approximately 198.17 g/mol. It has a pKa of about 3.5 and is slightly soluble in water. It is chemically reactive, particularly towards nucleophiles and bases, and can undergo polymerization under certain conditions.

(2E)-3-(4-Methoxyphenyl)acrylic acid can be synthesized by reacting 4-methoxybenzaldehyde with acrylic anhydride in the presence of a Lewis acid catalyst such as aluminum chloride. The reaction typically proceeds with good yield and selectivity, though careful control of reaction conditions is necessary to avoid side products.

(2E)-3-(4-Methoxyphenyl)acrylic acid is used in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry as a monomer for polymerization processes, and in the sensor industry for the development of chemical sensors. It is also used in the semiconductor industry for specific applications.

PPE required when handling (2E)-3-(4-Methoxyphenyl)acrylic acid includes gloves, goggles, and a lab coat. The substance should be handled in a fume hood. Spills should be carefully cleaned up using absorbent materials, and the area should be well ventilated. Refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.