Compound Q&A

How is (2E)-3-(4-Methoxyphenyl)acrylic acid (CAS: 943-89-5) typically synthesized?

Answer

(2E)-3-(4-Methoxyphenyl)acrylic acid
(2E)-3-(4-Methoxyphenyl)acrylic acid can be synthesized by reacting 4-methoxybenzaldehyde with acrylic anhydride in the presence of a Lewis acid catalyst such as aluminum chloride. The reaction typically proceeds with good yield and selectivity, though careful control of reaction conditions is necessary to avoid side products.

About

CAS No 943-89-5
English Name (2E)-3-(4-Methoxyphenyl)acrylic acid
Molecular Formula C10H10O3
Molecular Weight 178.19 g/mol
SMILES COc1ccc(/C=C/C(=O)O)cc1
InChIKey AFDXODALSZRGIH-QPJJXVBHSA-N
Last Updated: 2025-10-07 19:42

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