Ethyl 5-nitro-1-benzofuran-2-carboxylate(CAS: 69404-00-8)

Ethyl 5-nitro-1-benzofuran-2-carboxylate (CAS: 69404-00-8) is a crystalline compound with a molecular weight of approximately 262.17 g/mol. It has low water solubility and is moderately soluble in organic solvents like ethanol and acetone. This compound is thermally stable but can react with strong bases and oxidizing agents. It is used in organic synthesis and as a building block for various pharmaceuticals and dyes.

Ethyl 5-nitro-1-benzofuran-2-carboxylate (CAS: 69404-00-8) is typically synthesized via the nitration of ethyl 1-benzofuran-2-carboxylate with nitronium tetrafluoroborate in the presence of a suitable catalyst. The reaction yields a high purity product with good selectivity and yield under controlled conditions. This method allows for the controlled introduction of the nitro group into the benzofuran ring.

Ethyl 5-nitro-1-benzofuran-2-carboxylate (CAS: 69404-00-8) is used in the pharmaceutical industry for the synthesis of drug intermediates and in the chemical industry for the production of dyes and other organic compounds. It also finds applications in the development of sensors and as a precursor in the semiconductor industry.

When handling Ethyl 5-nitro-1-benzofuran-2-carboxylate (CAS: 69404-00-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly cleaned. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.