Compound Q&A
How is Ethyl 5-nitro-1-benzofuran-2-carboxylate (CAS: 69404-00-8) typically synthesized?
Answer
Ethyl 5-nitro-1-benzofuran-2-carboxylate (CAS: 69404-00-8) is typically synthesized via the nitration of ethyl 1-benzofuran-2-carboxylate with nitronium tetrafluoroborate in the presence of a suitable catalyst. The reaction yields a high purity product with good selectivity and yield under controlled conditions. This method allows for the controlled introduction of the nitro group into the benzofuran ring.
About
CAS No
69404-00-8
English Name
Ethyl 5-nitro-1-benzofuran-2-carboxylate
Molecular Formula
C11H9NO5
Molecular Weight
235.19 g/mol
SMILES
CCOC(=O)C1=CC2=C(O1)C=CC(=C2)[N+](=O)[O-]
InChIKey
ATHBGWVHAWGMAL-UHFFFAOYSA-N
Last Updated: 2026-03-16 21:46
