Dimethyl propylmalonate(CAS: 14035-96-2)

Dimethyl propylmalonate (CAS: 14035-96-2) is a colorless to slightly yellowish crystalline solid. It has a molecular weight of approximately 204.23 g/mol. The compound is soluble in organic solvents like ethanol and acetone but has low solubility in water. It is reactive towards nucleophiles and can undergo esterification and ester hydrolysis reactions.

Dimethyl propylmalonate (CAS: 14035-96-2) is synthesized by the reaction of propylmalonic acid with dimethyl sulfate. This process involves a nucleophilic substitution reaction where the carboxylic acid group of propylmalonic acid is methylated. The reaction is typically carried out in the presence of a strong base such as sodium hydride or potassium hydroxide.

Dimethyl propylmalonate (CAS: 14035-96-2) is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry as a monomer or additive. Additionally, it finds applications in the production of electronic materials and in the development of chemical sensors due to its reactivity and specific functional groups.

When handling Dimethyl propylmalonate (CAS: 14035-96-2), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. Storage should be in a cool, dry place away from heat sources and direct sunlight. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.