3-Hydroxy-4-iodobenzoic acid(CAS: 58123-77-6)

3-Hydroxy-4-iodobenzoic acid is a crystalline solid with a molecular weight of approximately 255.01 g/mol. It has a solubility of about 1.5 g/L in water at 25°C. The compound is relatively stable under normal conditions but can react with bases to form sodium salts. It is also prone to hydrolysis under acidic conditions.

3-Hydroxy-4-iodobenzoic acid is typically synthesized via the iodination of 3-hydroxybenzoic acid. This process often involves using N-iodosuccinimide (NIS) as the iodinating agent in the presence of a base such as sodium hydroxide. The reaction is carried out in an aqueous medium, and the yield can be improved by using appropriate conditions and solvents.

3-Hydroxy-4-iodobenzoic acid is used in various industries. It is particularly relevant in the pharmaceutical industry for the synthesis of certain drugs. Additionally, it can be used in the production of sensors and as a raw material in the polymer industry for the development of novel materials with specific properties.

When handling 3-Hydroxy-4-iodobenzoic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, well-ventilated area away from direct sunlight. Fume hoods should be used when performing synthesis or handling the compound. In case of a spill, it should be immediately cleaned up using appropriate chemicals and methods. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.