1,3-Bis(2-isocyanato-2-propanyl)benzene(CAS: 2778-42-9)

1,3-Bis(2-isocyanato-2-propanyl)benzene (CAS: 2778-42-9) is a solid crystalline compound with a molecular weight of approximately 276.27 g/mol. It is poorly soluble in water but soluble in organic solvents such as dichloromethane and acetone. The compound exhibits strong reactivity, particularly towards nucleophiles and hydrolysis under basic conditions.

1,3-Bis(2-isocyanato-2-propanyl)benzene is typically synthesized via the reaction of 1,3-bis(bromomethyl)benzene with phosgene in the presence of a catalyst, such as anhydrous zinc chloride. The reaction provides high selectivity and yields up to 90% of the desired product.

1,3-Bis(2-isocyanato-2-propanyl)benzene (CAS: 2778-42-9) is used in various industries, including pharmaceuticals, where it serves as a building block for complex molecules. It is also utilized in the production of polymers for coatings and adhesives, and in the development of sensors and semiconductors.

When handling 1,3-Bis(2-isocyanato-2-propanyl)benzene (CAS: 2778-42-9), it is essential to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure the use of a fume hood during preparation. Spills should be contained and cleaned up using appropriate absorbent materials. Refer to the safety data sheet (SDS) for detailed safety information and emergency procedures.