1,3-Benzothiazole-6-carboxylic acid(CAS: 3622-35-3)

1,3-Benzothiazole-6-carboxylic acid (CAS: 3622-35-3) is a crystalline solid with a molecular weight of approximately 200.22 g/mol. It has a solubility of around 0.2 g/L in water. Chemically, it is moderately reactive towards nucleophiles and can undergo esterification or amidation reactions. It can form complexes with metals and undergo condensation reactions with ammonia.

1,3-Benzothiazole-6-carboxylic acid can be synthesized by the condensation of benzothiazole with a carboxylic acid chloride or anhydride. Common catalysts include imidazole or triethylamine. The reaction involves the formation of an ester or amide bond, typically with high selectivity and good yield.

1,3-Benzothiazole-6-carboxylic acid (CAS: 3622-35-3) is used in pharmaceuticals for the synthesis of certain drugs, in polymers as a stabilizer, and in sensors for detecting specific analytes. It also finds applications in the synthesis of semiconductors and as a reagent in organic chemistry.

When handling 1,3-Benzothiazole-6-carboxylic acid (CAS: 3622-35-3), proper personal protective equipment (PPE) such as gloves and safety glasses should be worn. The substance should be handled in a fume hood to avoid inhalation of dust or vapors. In case of a spill, it should be handled according to the safety data sheet (SDS). Storage should be in a cool, dry place away from direct sunlight and incompatible materials.