(2-Aminophenyl)acetonitrile(CAS: 2973-50-4)

(2-Aminophenyl)acetonitrile (CAS: 2973-50-4) is a crystalline compound with a molecular weight of approximately 162.17 g/mol. It has a low solubility in water (0.4 g/L at 25°C) but is soluble in organic solvents such as ethanol and acetone. The compound is moderately reactive, showing some reactivity towards nucleophiles and electrophiles. It is stable under normal storage conditions but should be protected from strong oxidizing agents and light.

(2-Aminophenyl)acetonitrile is typically synthesized via the reaction of 2-aminophenol with acetonitrile in the presence of a base such as sodium hydroxide. The reaction is carried out in an organic solvent at elevated temperature, and the product is isolated by filtration and recrystallization. The yield is typically around 70%-80%, and the selectivity is good, with minimal side products formed.

(2-Aminophenyl)acetonitrile (CAS: 2973-50-4) is primarily used in the pharmaceutical industry as a precursor for the synthesis of various drug compounds. It also finds applications in the polymer industry for the modification of polymer properties, in the sensor industry for developing gas sensors, and in the semiconductor industry for the production of organic semiconductors.

When handling (2-Aminophenyl)acetonitrile (CAS: 2973-50-4), it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS/SDS) for detailed safety information and emergency procedures.