Compound Q&A

How is (2-Aminophenyl)acetonitrile (CAS: 2973-50-4) typically synthesized?

Answer

(2-Aminophenyl)acetonitrile
(2-Aminophenyl)acetonitrile is typically synthesized via the reaction of 2-aminophenol with acetonitrile in the presence of a base such as sodium hydroxide. The reaction is carried out in an organic solvent at elevated temperature, and the product is isolated by filtration and recrystallization. The yield is typically around 70%-80%, and the selectivity is good, with minimal side products formed.

About

CAS No 2973-50-4
English Name (2-Aminophenyl)acetonitrile
Molecular Formula C8H8N2
Molecular Weight 121.18 g/mol
SMILES C1=CC=C(C(=C1)CC#N)N
InChIKey LMDPYYUISNUGGT-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:30

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