m-PEG3-SH(CAS: 31521-83-2)

m-PEG3-SH (CAS: 31521-83-2) is a hydroxyl-terminated polyethylene glycol (PEG), with a molecular weight of approximately 2000 Da. It is a clear, colorless liquid at room temperature. It has good solubility in water and organic solvents. Chemically, it is highly reactive due to the presence of the thiol (-SH) group, making it useful for thiolation reactions in various applications.

m-PEG3-SH (CAS: 31521-83-2) is synthesized by a two-step process. First, PEG is derivatized with a thiol group through reaction with maleimide-PEG, followed by reduction of the maleimide to a thiol. This method provides a high degree of selectivity and yield, and often uses sodium borohydride as a reducing agent.

m-PEG3-SH (CAS: 31521-83-2) is widely used in the pharmaceutical, polymer, and sensor industries. In pharmaceuticals, it serves as a stabilizer and drug delivery agent. In polymers, it is used for functionalization and modification. In sensors, it enhances sensitivity and selectivity. Additionally, it plays a role in semiconductor applications for surface modification.

When handling m-PEG3-SH (CAS: 31521-83-2), proper personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. It is flammable and should be stored in a cool, dry place away from heat sources. Always use a fume hood during mixing and reaction steps. In case of spill, absorb with an inert material and dispose of according to local regulations. Refer to the Safety Data Sheet (SDS) for more detailed information.