2,2,6,6-Tetramethyl-4-piperidinone hydrochloride (1:1)(CAS: 33973-59-0)

2,2,6,6-Tetramethyl-4-piperidinone hydrochloride (CAS: 33973-59-0) is a crystalline compound with a molecular weight of approximately 228.7 g/mol. It has a solubility of about 60 g/L in water and is slightly soluble in ethanol. It is chemically stable but reacts with strong oxidizing agents. It is a common intermediate in organic synthesis and is used as a stabilizer in various applications.

2,2,6,6-Tetramethyl-4-piperidinone hydrochloride is typically synthesized by the reaction of 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) with hydrochloric acid. The process involves the protonation of TEMPO, followed by chlorination. Suitable catalysts and reagents include hydrochloric acid and chlorine gas, with high selectivity and moderate yield.

2,2,6,6-Tetramethyl-4-piperidinone hydrochloride (CAS: 33973-59-0) is widely used in the pharmaceutical, polymer, and semiconductor industries. It serves as a stabilizer in pharmaceutical formulations, enhances the stability of polymers, and acts as a scavenger in semiconductor manufacturing processes.

When handling 2,2,6,6-Tetramethyl-4-piperidinone hydrochloride (CAS: 33973-59-0), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Store in a cool, dry place away from direct sunlight. Use a fume hood for any manipulations, and follow proper spill procedures as outlined in the Safety Data Sheet (SDS).