1,2-Dihydro Dexamethasone(CAS: 426-17-5)

1,2-Dihydro Dexamethasone is a white crystalline powder with a molecular weight of approximately 476.65 g/mol. It is slightly soluble in water and ethanol. Chemically, it is highly reactive due to the presence of functional groups such as the hydroxyl and methyl groups. It undergoes hydrolysis and oxidation readily.

1,2-Dihydro Dexamethasone is typically synthesized by reducing dexamethasone with sodium borohydride or lithium aluminum hydride. The reaction involves the reduction of the C17-ester to a hydroxyl group, resulting in a highly selective and efficient synthesis with good yields.

1,2-Dihydro Dexamethasone is primarily used in the pharmaceutical industry for the production of corticosteroid medications. It is also utilized in research and development for its anti-inflammatory and immunosuppressive properties.

When handling 1,2-Dihydro Dexamethasone, it is crucial to use personal protective equipment (PPE) such as gloves and safety goggles. Work in a well-ventilated area or fume hood to minimize exposure. Spills should be cleaned up using appropriate procedures as outlined in the Safety Data Sheet (SDS).