2-(3,4-Diethoxyphenyl)ethanamine(CAS: 61381-04-2)

2-(3,4-Diethoxyphenyl)ethanamine (CAS: 61381-04-2) is a white crystalline solid with a molecular weight of approximately 258.35 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. This compound is moderately reactive due to the presence of electrophilic aromatic groups. It exhibits a pKa of around 4.5, indicating it is a weak base.

2-(3,4-Diethoxyphenyl)ethanamine is typically synthesized through a multistep process involving the direct alkylation of aniline with 3,4-dimethoxybenzene, followed by alkylation with ethyl bromide. The reaction is catalyzed by a strong acid like sulfuric acid, and the yield is moderate, around 60-70%. The reaction is carried out under reflux conditions for several hours, and the product is purified by recrystallization.

2-(3,4-Diethoxyphenyl)ethanamine (CAS: 61381-04-2) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for the development of polymeric materials with specific properties. Additionally, it has applications in the sensor industry for the production of gas sensors and in the semiconductor industry as a precursor for electronic materials.

When handling 2-(3,4-Diethoxyphenyl)ethanamine (CAS: 61381-04-2), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for specific handling and disposal instructions.