2-Iodo-5-methylpyridine(CAS: 22282-62-8)

2-Iodo-5-methylpyridine (CAS: 22282-62-8) is a crystalline solid with a molecular weight of approximately 229.02 g/mol. It has moderate solubility in common organic solvents like ethanol and acetone. The compound shows limited reactivity but can undergo substitution reactions with good yield. It is stable under normal temperature and pressure conditions.

2-Iodo-5-methylpyridine is typically synthesized through a reaction between 5-methylpyridine and iodine in the presence of a catalyst such as iron trifluoromethanesulfonate. The method yields a high percentage of the desired product with good selectivity. The reaction is carried out at room temperature and atmospheric pressure.

2-Iodo-5-methylpyridine (CAS: 22282-62-8) finds applications in pharmaceuticals, particularly as a potential intermediate in the synthesis of certain drugs. It is also used in the development of sensors and in the synthesis of materials for semiconductor applications.

When handling 2-Iodo-5-methylpyridine (CAS: 22282-62-8), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately with appropriate absorbent materials, and the area should be thoroughly ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.