Methyl 6-bromo-2-pyridinecarboxylate(CAS: 26218-75-7)

Methyl 6-bromo-2-pyridinecarboxylate (CAS: 26218-75-7) is a crystalline solid with a molecular weight of approximately 228.03 g/mol. It has a low solubility in water but is soluble in most organic solvents. This compound is moderately reactive, particularly towards nucleophiles and reducing agents. It can form complexes with metal ions and may undergo nucleophilic substitution reactions.

Methyl 6-bromo-2-pyridinecarboxylate is typically synthesized through the reaction of methyl 2-pyridinecarboxylate with bromine in the presence of a base such as sodium hydroxide. This process yields the target compound with good selectivity and a yield of around 70-80%. The reaction is conducted at room temperature and under an inert atmosphere.

Methyl 6-bromo-2-pyridinecarboxylate (CAS: 26218-75-7) is primarily used in the pharmaceutical industry for the synthesis of intermediates and bioactive compounds. It also has applications in the polymer industry for the modification of polymer properties and in the semiconductor industry as a precursor for various materials.

When handling Methyl 6-bromo-2-pyridinecarboxylate (CAS: 26218-75-7), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be handled in a well-ventilated area or a fume hood to minimize exposure to bromine and other reaction byproducts. In case of a spill, use appropriate absorbent materials and follow the safety data sheet (SDS) for disposal instructions to ensure proper handling and environmental safety.