Colistin sulfate(CAS: 1264-72-8)

Colistin sulfate is an antibiotic compound with the CAS number 1264-72-8. It is a sulfate salt of colistin, a cyclic lipopeptide antibiotic primarily used for treating serious gram-negative bacterial infections. Colistin sulfate has a molecular formula of C₃₄H₆₃NO₁₃S₂ and is known for its cationic surfactant properties, which contribute to its antimicrobial activity. It is commonly available as a powder or solution and is used in veterinary medicine and human healthcare.

Colistin sulfate (CAS: 1264-72-8) is primarily used in veterinary medicine to treat bacterial infections in animals, especially in poultry and swine. It is also employed in human medicine for severe infections caused by multidrug-resistant gram-negative bacteria. Additionally, it finds applications in research for studying antimicrobial mechanisms and in industrial settings for producing pharmaceutical products. Its use in food production is limited to specific therapeutic contexts under regulatory guidelines.

Colistin sulfate (CAS: 1264-72-8) is generally considered safe when used as directed, but it requires careful handling due to its potential toxicity. Prolonged use or high doses may lead to nephrotoxicity and neurotoxicity. Safety standards emphasize proper dosing, monitoring, and adherence to guidelines to minimize adverse effects. Protective measures include using personal protective equipment and following standard operating procedures for handling pharmaceutical compounds.

Colistin sulfate (CAS: 1264-72-8) should be stored in a cool, dry place away from direct sunlight. It is typically kept in airtight containers to prevent moisture absorption and degradation. The recommended storage temperature is between 15°C to 25°C, and it should be protected from humidity and light exposure. Proper storage ensures stability and maintains the compound's effectiveness over time.