(2S)-2-Oxiranylmethyl 4-methylbenzenesulfonate(CAS: 70987-78-9)

(2S)-2-Oxiranylmethyl 4-methylbenzenesulfonate is a crystalline compound with a molecular weight of approximately 272.27 g/mol. It is poorly soluble in water but soluble in common organic solvents like dichloromethane and ethanol. The compound is moderately reactive and susceptible to hydrolysis under basic conditions. It is stable under normal storage conditions but should be stored in a cool, dry place away from strong acids and bases.

(2S)-2-Oxiranylmethyl 4-methylbenzenesulfonate is typically synthesized via a condensation reaction between 4-methylbenzenesulfonyl chloride and (2S)-2-oxiranyl methyl ether. The reaction is catalyzed by a strong base such as potassium tert-butoxide and proceeds with high selectivity and yield. The resulting product is isolated by washing with aqueous acid and recrystallization from a suitable solvent.

(2S)-2-Oxiranylmethyl 4-methylbenzenesulfonate is used in the pharmaceutical industry as a synthetic intermediate for the production of certain drugs. It is also employed in the polymer industry for the synthesis of functional polymers and in the semiconductor industry for the development of photoresists and other materials. Additionally, it has applications in the production of sensors and in the modification of materials for specific chemical and physical properties.

When handling (2S)-2-Oxiranylmethyl 4-methylbenzenesulfonate, it is essential to use appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood due to its potential for inhalation hazards. In case of a spill, it should be carefully cleaned up using appropriate absorbents, and the area should be washed with water. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.