4-chloro-5-iodo-pyridin-2-amine(CAS: 670253-37-9)

4-Chloro-5-iodo-pyridin-2-amine (CAS: 670253-37-9) is a crystalline solid. Its molecular weight is approximately 297.02 g/mol. This compound has limited solubility in water but is more soluble in organic solvents like DMSO and DMA. It is mildly reactive towards nucleophiles. It is stable under normal conditions but should be stored in a cool, dry place to prevent hydrolysis.

4-Chloro-5-iodo-pyridin-2-amine (CAS: 670253-37-9) can be synthesized by reacting 5-chloro-2-pyridamine with sodium iodide in the presence of a base such as potassium carbonate. This reaction is typically carried out in a suitable solvent like N,N-dimethylformamide (DMF) at room temperature. The yield can be improved by optimizing the reaction conditions and using high-purity reagents.

4-Chloro-5-iodo-pyridin-2-amine (CAS: 670253-37-9) is primarily used in pharmaceuticals, specifically in drug synthesis for antimicrobial and antiviral compounds. It is also explored for its potential applications in sensor technology and as a precursor in the development of novel materials.

When handling 4-chloro-5-iodo-pyridin-2-amine (CAS: 670253-37-9), ensure proper personal protective equipment (PPE) is worn, including gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood due to its potential for volatility. Spills should be managed carefully, using absorbent materials and disposing of them according to local regulations. Refer to the safety data sheet (SDS) for detailed handling and disposal information.