(2-Nitrophenyl)acetic acid(CAS: 3740-52-1)

(2-Nitrophenyl)acetic acid is a crystalline solid with a molecular weight of approximately 207.08 g/mol. It has a low solubility in water but good solubility in organic solvents. The compound is moderately reactive, particularly towards nucleophilic substitution reactions. It is commonly used in various chemical syntheses and as a reagent in analytical chemistry.

(2-Nitrophenyl)acetic acid can be synthesized by esterification of 2-nitrophenol with acetic anhydride. The reaction is conducted under mild conditions, and the product can be isolated by filtration and recrystallization. This method provides a yield of around 85-90%.

(2-Nitrophenyl)acetic acid is primarily used in the pharmaceutical, polymer, and analytical chemistry industries. It serves as a precursor in the synthesis of various chemical compounds and reagents. Additionally, it finds applications in the development of sensors and as a component in some semiconductor processes.

When handling (2-Nitrophenyl)acetic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly ventilated. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.