5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide(CAS: 53714-56-0)

5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide (CAS: 53714-56-0) is a cyclic heptapeptide. It crystallizes in the form of a white solid. The molecular weight is approximately 1698.4 g/mol. This compound is poorly soluble in water but soluble in organic solvents such as methanol and ethanol. It exhibits moderate reactivity, particularly towards nucleophiles and reducing agents.

5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide (CAS: 53714-56-0) is synthesized through solid-phase peptide synthesis (SPPS). Common methods include using Rink amide or Fmoc (fluorenylmethyloxycarbonyl) resin. This peptide is synthesized using standard coupling reagents such as HBTU (1-hydroxybenzotriazole, 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide), with high selectivity and yield. The final product is typically deprotected and cleaved from the resin using strong acid, followed by purification.

5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide (CAS: 53714-56-0) is primarily used in the pharmaceutical industry for drug discovery and development. It also finds applications in biotechnology, where it is used in the development of biosensors and in polymer-based materials for specific industrial applications. Additionally, this compound can be utilized in the semiconductor industry for specific functionalization purposes.

When handling 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide (CAS: 53714-56-0), it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Handle this compound in a well-ventilated area or fume hood to avoid inhalation. In case of a spill, immediately clean it up using appropriate absorbent materials and wash the area thoroughly. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.