Compound Q&A
How is 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide (CAS: 53714-56-0) typically synthesized?
Answer
5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide (CAS: 53714-56-0) is synthesized through solid-phase peptide synthesis (SPPS). Common methods include using Rink amide or Fmoc (fluorenylmethyloxycarbonyl) resin. This peptide is synthesized using standard coupling reagents such as HBTU (1-hydroxybenzotriazole, 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide), with high selectivity and yield. The final product is typically deprotected and cleaved from the resin using strong acid, followed by purification.
About
CAS No
53714-56-0
English Name
5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide
Molecular Formula
C59H84N16O12
Molecular Weight
1209.42 g/mol
SMILES
CCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6
InChIKey
GFIJNRVAKGFPGQ-LIJARHBVSA-N
Last Updated: 2025-09-22 19:21
