2-Amino-6-fluorobenzoic acid(CAS: 434-76-4)

2-Amino-6-fluorobenzoic acid is a crystalline solid with a molecular weight of approximately 191.07 g/mol. It has a solubility of about 1.8 g/L in water at 20°C. Chemically, it is moderately reactive, primarily undergoing nucleophilic substitution and condensation reactions. It is sensitive to light and moisture, and should be stored in a dry, cool place away from direct sunlight.

2-Amino-6-fluorobenzoic acid is commonly synthesized through the reaction of 6-fluorobenzoic acid with aniline in the presence of a base like sodium hydroxide. The reaction is selective and yields up to 90% of the desired product, making it a viable method for industrial production.

2-Amino-6-fluorobenzoic acid is used in the pharmaceutical industry for the synthesis of certain drugs, and in the polymer industry as a precursor for the production of various materials. It also finds applications in the semiconductor industry as a dopant and in the development of sensors.

When handling 2-Amino-6-fluorobenzoic acid, it is essential to use appropriate personal protective equipment such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from light and moisture. In case of a spill, it is recommended to use appropriate absorbents and follow local safety guidelines. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.