(S)-3-(Benzyloxy)-2-((tert-butoxycarbonyl)amino)propanoic acid(CAS: 23680-31-1)

(S)-3-(Benzyloxy)-2-((tert-butoxycarbonyl)amino)propanoic acid is a white crystalline solid with a molecular weight of approximately 340.47 g/mol. It has a low solubility in water but is more soluble in organic solvents. This compound is reactive, particularly towards nucleophiles, and can undergo esterification and amidation reactions. It is often used in peptide synthesis due to its stability and reactivity.

(S)-3-(Benzyloxy)-2-((tert-butoxycarbonyl)amino)propanoic acid is typically synthesized via a multi-step process involving the protection of the amino group with tert-butoxycarbonyl and the introduction of the benzyloxy group. Common methods include the use of reagents like tert-butyloxycarbonyl chloride and benzylic alcohol, followed by purification techniques such as column chromatography. This compound is often synthesized with high yield and good selectivity.

(S)-3-(Benzyloxy)-2-((tert-butoxycarbonyl)amino)propanoic acid is primarily used in the pharmaceutical industry for peptide synthesis and drug development. It is also relevant in the polymer industry for synthesizing functional polymers and in the sensor industry for developing biosensors. Additionally, it may have applications in semiconductors, although its use in this field is less common.

When handling (S)-3-(Benzyloxy)-2-((tert-butoxycarbonyl)amino)propanoic acid, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area, preferably under a fume hood. Spills should be cleaned up immediately using appropriate procedures, and the SDS (Safety Data Sheet) should be referenced for specific handling instructions. Storage should be in a cool, dry place away from moisture and direct sunlight.