Benzyl 4-(hydroxymethyl)-1-piperidinecarboxylate(CAS: 122860-33-7)

Benzyl 4-(hydroxymethyl)-1-piperidinecarboxylate is a solid with a crystalline form. Its molecular weight is approximately 246.27 g/mol. The compound has a low solubility in water but is soluble in common organic solvents. It is reactive towards nucleophiles, showing moderate reactivity in organic synthesis. The compound has a pKa of about 13.5.

Benzyl 4-(hydroxymethyl)-1-piperidinecarboxylate is typically synthesized via the reaction of benzyl 4-formyl-1-piperidinecarboxylate with sodium hydroxide in ethanol. The reaction is carried out under mild conditions, resulting in a high yield. The reaction is selective and produces pure product with excellent yield.

Benzyl 4-(hydroxymethyl)-1-piperidinecarboxylate finds applications in the pharmaceutical industry for the synthesis of various drugs. It is also used in the polymer industry as a monomer for the development of new polymers. Additionally, it has potential uses in the sensor and semiconductor industries due to its chemical properties.

When handling Benzyl 4-(hydroxymethyl)-1-piperidinecarboxylate, proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be used. The compound should be handled in a fume hood to avoid inhalation. Spills should be cleaned up carefully using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the Material Safety Data Sheet (MSDS) for specific safety guidelines.