Atractyloside A(CAS: 126054-77-1)

Atractyloside A (CAS: 126054-77-1) is a crystalline compound with a molecular weight of approximately 428.35 g/mol. It is only slightly soluble in water and ethanol, but soluble in methanol. Atractyloside A is reactive towards acidic conditions, particularly in the presence of hydrochloric acid. It is stable under neutral and basic conditions but should be stored in a desiccator to avoid moisture absorption.

Atractyloside A (CAS: 126054-77-1) is typically synthesized through semi-synthetic methods from natural sources, such as the roots of Atractylodes macrocephala. The synthesis involves a series of enzymatic and chemical transformations, including hydroxylation and glycosylation steps. Commonly used catalysts include enzymes like β-glucosidase and hydrogenation catalysts. The overall yield is moderate, around 10-20%, with high purity achievable through column chromatography.

Atractyloside A (CAS: 126054-77-1) is primarily used in the pharmaceutical industry due to its potential medicinal properties. It has shown promise in the treatment of diabetes, cardiovascular diseases, and certain types of cancer. Additionally, it finds applications in the food industry as a potential antioxidant and in the development of new sensors and semiconductors.

When handling Atractyloside A (CAS: 126054-77-1), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood due to its reactivity towards acids. Spills should be immediately cleaned up using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.