3-Oxoolean-12-en-28-oic acid(CAS: 17990-42-0)

3-Oxoolean-12-en-28-oic acid is a white to off-white crystalline solid with a molecular weight of approximately 422.44 g/mol. It is poorly water-soluble but soluble in organic solvents like chloroform and methanol. Chemically, it is reactive towards esterification and can undergo hydrogenation to form 3-oxoolean-12-ene-28-oic acid. It also exhibits reactivity towards amide formation and esterification reactions.

3-Oxoolean-12-en-28-oic acid is typically synthesized through the oxidation of 3-oxoolean-12-ene-28-aldehyde followed by acid catalyzed condensation. The synthesis often involves the use of chromic acid or potassium permanganate for oxidation, and hydrochloric acid for the condensation step. The overall yield is moderate to good, and the selectivity is high.

3-Oxoolean-12-en-28-oic acid is used in the pharmaceutical industry for its biological activity, particularly in the development of potential anti-inflammatory and anticancer drugs. It is also used in the polymer industry as a precursor for polymer synthesis and in the production of functionalized polymers. Additionally, it has applications in the sensor technology and semiconductor industries.

When handling 3-Oxoolean-12-en-28-oic acid, it is essential to use personal protective equipment (PPE) including gloves, goggles, and a lab coat. Store it in a well-ventilated area away from heat and sources of ignition. In case of spills, clean up with appropriate absorbent materials and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.