Ethyl 2-(6-quinolinyl)propanoate(CAS: 1193317-61-1)

Ethyl 2-(6-quinolinyl)propanoate (CAS: 1193317-61-1) is a colorless to light yellow liquid with a molecular weight of approximately 232.29 g/mol. It has a high solubility in organic solvents like ethanol and acetone but is practically insoluble in water. The compound is moderately reactive towards nucleophiles and can undergo ester hydrolysis under acidic or basic conditions. It is stable under normal storage conditions but should be protected from moisture and light.

Ethyl 2-(6-quinolinyl)propanoate (CAS: 1193317-61-1) is typically synthesized by the reaction of 2-bromopropanol with 6-quinolinecarboxylic acid in the presence of a base like potassium carbonate. The reaction is carried out in an organic solvent such as dimethylformamide (DMF) at elevated temperatures, typically around 80°C. Stoichiometric amounts of the reagents and appropriate catalysts are used to achieve high yields and good selectivity.

Ethyl 2-(6-quinolinyl)propanoate (CAS: 1193317-61-1) is used in the pharmaceutical industry as a precursor for the synthesis of certain quinoline-based drugs. It is also utilized in the production of functional materials such as sensors and semiconductors due to its electronic properties. Additionally, it is employed in the polymer industry for the modification of polymer properties and in the development of new polymer-based materials.

When handling Ethyl 2-(6-quinolinyl)propanoate (CAS: 1193317-61-1), appropriate personal protective equipment (PPE) should be worn, including gloves, safety glasses, and a lab coat. The compound should be handled in a well-ventilated area or under a fume hood due to its volatility and potential for inhalation. Spills should be cleaned up with appropriate absorbents and disposed of according to local regulations. It is important to refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.