(1R)-1-(5-Fluoro-2-iodophenyl)ethanol(CAS: 1454852-98-2)

(1R)-1-(5-Fluoro-2-iodophenyl)ethanol is a colorless to light yellow liquid with a molecular weight of approximately 309.97 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. The compound is relatively stable but can react with reducing agents. It is used as an intermediate in organic synthesis.

(1R)-1-(5-Fluoro-2-iodophenyl)ethanol can be synthesized via the reaction of 2-iodo-5-fluorobenzaldehyde with ethanol. The reaction is typically catalyzed by a base like sodium ethoxide. The yield is around 70-80%, and the product is isolated by recrystallization. The reaction is selective and efficient for this specific compound.

(1R)-1-(5-Fluoro-2-iodophenyl)ethanol is primarily used in the pharmaceutical industry as an intermediate for synthesizing various drugs. It can also be used in polymer chemistry for developing new materials and in the field of chemical sensors for detecting specific compounds.

When handling (1R)-1-(5-Fluoro-2-iodophenyl)ethanol, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure the use of a fume hood during the handling of the compound. In case of a spill, neutralize any potential reaction products and clean up with appropriate chemicals. Refer to the Safety Data Sheet (SDS) for detailed guidelines and emergency procedures.