1-Fluoro-2-nitro-4-(trifluoromethyl)benzene(CAS: 367-86-2)

1-Fluoro-2-nitro-4-(trifluoromethyl)benzene (CAS 367-86-2) is a crystalline solid with a molecular weight of approximately 266.02 g/mol. It is poorly soluble in water but soluble in common organic solvents like dichloromethane and acetonitrile. The compound is highly reactive, particularly towards nucleophilic substitution and reduction reactions.

1-Fluoro-2-nitro-4-(trifluoromethyl)benzene is typically synthesized via the nitration of 1-fluoro-4-(trifluoromethyl)benzene followed by nitration. This process involves the use of nitric acid and sulfuric acid as reagents, and the reaction is carried out under controlled conditions to ensure high selectivity and yield.

1-Fluoro-2-nitro-4-(trifluoromethyl)benzene is used in various industries, particularly in pharmaceuticals for the synthesis of drug intermediates, and in the production of sensors and semiconductors. It is also utilized in the polymer industry for the development of specialized polymers with enhanced properties.

When handling 1-Fluoro-2-nitro-4-(trifluoromethyl)benzene (CAS 367-86-2), it is crucial to wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbents, and the material safety data sheet (MSDS/SDS) should be consulted for proper disposal and emergency response procedures.