p-Toluenesulfonyl azide(CAS: 941-55-9)

p-Toluenesulfonyl azide (CAS: 941-55-9) is a crystalline white solid with a molecular weight of approximately 213.19 g/mol. It has a melting point of 118-121°C and is soluble in organic solvents like dichloromethane and acetone. Chemically, it is highly reactive due to the presence of a nitroso group, making it useful in various chemical reactions.

p-Toluenesulfonyl azide is typically synthesized by the reaction of toluenesulfonyl chloride with sodium azide in an aqueous medium. The process is carried out under mild conditions and yields a high purity product with good selectivity and yield. The reaction is catalyzed by a base, such as sodium carbonate, and is followed by purification using recrystallization.

p-Toluenesulfonyl azide (CAS: 941-55-9) is primarily used in the pharmaceutical industry for the synthesis of various biologically active compounds. It is also utilized in the polymer industry for the modification of polymers and in the development of sensors and semiconductors due to its reactivity and functional groups.

When handling p-Toluenesulfonyl azide (CAS: 941-55-9), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always consult a Safety Data Sheet (SDS) for detailed safety instructions and emergency procedures.