5-Fluoro-1,3-thiazol-2-amine hydrochloride (1:1)(CAS: 745053-64-9)

5-Fluoro-1,3-thiazol-2-amine hydrochloride (CAS: 745053-64-9) is a crystalline compound with a molecular weight of approximately 214.6 g/mol. It has a solubility of about 25 g/L in water and is slightly soluble in ethanol. The compound is stable under normal conditions but reacts with bases to form the corresponding amine. It is typically used in pharmaceuticals and as a reagent in organic synthesis.

5-Fluoro-1,3-thiazol-2-amine hydrochloride (CAS: 745053-64-9) is commonly synthesized via the reaction of thiosemicarbazide with 5-fluoro-1,3-thiazol-2-one in the presence of an acid catalyst. The reaction typically yields high purity product with good selectivity and a high yield of over 90%. The process requires careful control of temperature and reaction time to achieve optimal results.

5-Fluoro-1,3-thiazol-2-amine hydrochloride (CAS: 745053-64-9) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also utilized in the sensor industry for its reactivity and in some organic synthesis applications. Its use in the semiconductor industry is limited but it can be explored for specific applications requiring its unique chemical properties.

When handling 5-Fluoro-1,3-thiazol-2-amine hydrochloride (CAS: 745053-64-9), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. This compound should be used in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up using proper laboratory techniques, and the Material Safety Data Sheet (MSDS) should be consulted for detailed safety information and emergency procedures.