Compound Q&A

How is 5-Fluoro-1,3-thiazol-2-amine hydrochloride (CAS: 745053-64-9) typically synthesized?

Answer

5-Fluoro-1,3-thiazol-2-amine hydrochloride (1:1)
5-Fluoro-1,3-thiazol-2-amine hydrochloride (CAS: 745053-64-9) is commonly synthesized via the reaction of thiosemicarbazide with 5-fluoro-1,3-thiazol-2-one in the presence of an acid catalyst. The reaction typically yields high purity product with good selectivity and a high yield of over 90%. The process requires careful control of temperature and reaction time to achieve optimal results.

About

English Name 5-Fluoro-1,3-thiazol-2-amine hydrochloride (1:1)
Molecular Formula C3H4ClFN2S
Molecular Weight 154.597 g/mol
SMILES C1=C(SC(=N1)N)F.Cl
InChIKey HUXNGTYNEWXYDM-UHFFFAOYSA-N
Last Updated: 2025-10-13 17:50

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