5-Bromo-6-chloro-1H-indol-3-yl butyrate(CAS: 873295-29-5)

5-Bromo-6-chloro-1H-indol-3-yl butyrate is a crystalline solid with a molecular weight of approximately 358.03 g/mol. It has limited water solubility (0.01 g/L at 20°C) and exhibits moderate reactivity with certain nucleophiles. The compound is stable under normal conditions but should be stored away from moisture and extreme temperatures.

5-Bromo-6-chloro-1H-indol-3-yl butyrate is typically synthesized via a multistep process involving the bromination and chlorination of indole followed by esterification with butyric anhydride. The reaction is conducted in the presence of a Lewis acid catalyst and proceeds with high selectivity and good yield.

5-Bromo-6-chloro-1H-indol-3-yl butyrate finds applications in the pharmaceutical industry for the development of novel bioactive compounds. It is also used in research for synthesizing other indole derivatives, which can be utilized in various fields such as polymers, sensors, and semiconductors.

When handling 5-Bromo-6-chloro-1H-indol-3-yl butyrate, it is essential to wear appropriate personal protective equipment (PPE), including gloves, lab coat, and safety goggles. The compound should be stored in a sealed container in a fume hood to minimize exposure. Spills should be cleaned up immediately with appropriate absorbents, and the area should be ventilated. Always refer to the Safety Data Sheet (SDS) for detailed safety information.