5-Methyl-2-phenyl-1,3-oxazole-4-carboxylic acid(CAS: 18735-74-5)

5-Methyl-2-phenyl-1,3-oxazole-4-carboxylic acid is a white crystalline solid with a molecular weight of 231.25 g/mol. It is slightly soluble in water but soluble in common organic solvents. Chemically, it is stable under normal conditions but can react with strong acids and bases. It exhibits characteristic acidic behavior due to the carboxylic acid group.

5-Methyl-2-phenyl-1,3-oxazole-4-carboxylic acid is synthesized through a multi-step process involving the condensation of 2-phenyl-1,3-oxazole with acetic anhydride followed by hydrolysis. The reaction is catalyzed by a suitable acid to enhance selectivity and yield, typically around 85-90%.

5-Methyl-2-phenyl-1,3-oxazole-4-carboxylic acid is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in polymer production, particularly in the development of functional polymers. Additionally, it is used in the fabrication of chemical sensors and semiconductors due to its unique chemical properties.

When handling 5-Methyl-2-phenyl-1,3-oxazole-4-carboxylic acid, it is important to use personal protective equipment (PPE) such as gloves and goggles. It should be stored in a dry, cool place away from direct sunlight and heat sources. In case of spills, neutralize with a base solution and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.