1-[4-(4-Propionyl-1-piperazinyl)-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h][1,6]naphthyridin-2(1H)-one(CAS: 1222998-36-8)

The compound has a crystalline form with a molecular weight of approximately 861.8 g/mol. It has low solubility in water but good solubility in organic solvents like DMSO and DMF. Chemically, it is moderately reactive, showing good stability under neutral conditions but can undergo degradation under acidic or basic conditions. It has moderate lipophilicity, making it suitable for certain pharmaceutical and chemical applications.

This compound is typically synthesized through a multi-step process involving condensation reactions and electrophilic aromatic substitution. Common synthetic methods include using 4-(4-propionyl-1-piperazinyl)-3-(trifluoromethyl)benzoic acid and 3-quinolinyl hydrazine as starting materials, with appropriate catalysts and reagents. The yield is generally around 60-70%, with good selectivity to the desired product.

This compound is used primarily in the pharmaceutical industry for its potential therapeutic applications. Additionally, it has some relevance in the polymer industry for use in polymer synthesis and modification. It may also be utilized in the development of sensors and semiconductors due to its unique chemical structure and properties.

When handling this compound, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure the use of a fume hood to minimize exposure to vapors. Store the compound in a cool, dry place away from direct sunlight. In case of a spill, immediately clean up using appropriate absorbent materials and follow the safety data sheet (SDS) for proper disposal. Always refer to the latest SDS for detailed safety information.