5-Methylisophthalic acid(CAS: 499-49-0)

5-Methylisophthalic acid (CAS: 499-49-0) is a white crystalline solid with a molecular weight of approximately 166.13 g/mol. It is slightly soluble in water, with a solubility of about 0.5 g/L at 25°C. This compound exhibits moderate reactivity, particularly in esterification reactions. It is used in the synthesis of polymers and pharmaceuticals.

5-Methylisophthalic acid is typically synthesized by the oxidation of 4-methylanisole using a suitable oxidizing agent such as potassium permanganate or sodium periodate. This process yields a mixture that can be purified by recrystallization or other separation techniques. The reaction is highly selective, providing good yields of the desired product.

5-Methylisophthalic acid (CAS: 499-49-0) is primarily used in the pharmaceutical and polymer industries. It serves as a precursor in the synthesis of various polymers and is also employed in the production of pharmaceuticals, particularly in the development of certain active pharmaceutical ingredients (APIs).

When handling 5-Methylisophthalic acid (CAS: 499-49-0), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and lab coat. Handle in a fume hood to avoid inhalation. Spills should be handled carefully, and the area should be thoroughly cleaned. Refer to the safety data sheet (SDS) for detailed handling and disposal information.