Ethyl 2-(3-bromophenyl)-1,3-thiazole-4-carboxylate(CAS: 786654-97-5)

Ethyl 2-(3-bromophenyl)-1,3-thiazole-4-carboxylate (CAS: 786654-97-5) is a crystalline solid with a molecular weight of approximately 383.04 g/mol. It has low solubility in water but is soluble in organic solvents such as ethanol and acetone. This compound is moderately reactive and can undergo substitution reactions. It is stable under normal conditions but requires handling in a fume hood to prevent inhalation exposure.

Ethyl 2-(3-bromophenyl)-1,3-thiazole-4-carboxylate (CAS: 786654-97-5) is typically synthesized through a multistep process involving the bromination of a phenyl group followed by coupling with 1,3-thiazole-4-carboxylic acid ethyl ester. Commonly used catalysts include thionyl chloride and triethylamine. The reaction yields a product with high selectivity and good yield, suitable for further chemical transformations.

Ethyl 2-(3-bromophenyl)-1,3-thiazole-4-carboxylate (CAS: 786654-97-5) is primarily used in the pharmaceutical industry for the synthesis of various drug candidates. It is also utilized in the development of sensors and semiconductors due to its unique chemical properties. Additionally, it may find applications in the polymer industry, although specific uses are limited.

When handling Ethyl 2-(3-bromophenyl)-1,3-thiazole-4-carboxylate (CAS: 786654-97-5), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to prevent inhalation exposure. Spills should be cleaned up using appropriate absorbents, and disposal should follow local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.