2'-O-Methylguanosine(CAS: 2140-71-8)

2'-O-Methylguanosine (CAS: 2140-71-8) is a nucleoside derivative where the 2' hydroxyl group of guanosine is replaced with a methyl group. Its chemical formula is C10H13N5O6, and it exhibits characteristics such as solubility in water, a white crystalline or powder appearance, and stability under controlled conditions. This compound is commonly used in molecular biology research and pharmaceutical applications due to its structural similarity to guanosine.

2'-O-Methylguanosine (CAS: 2140-71-8) is primarily used in pharmaceuticals as a component in drug development targeting nucleic acid interactions. It also serves in biotechnology for RNA modification studies, in research for synthetic biology applications, and in the production of nucleoside analogs. Additionally, it may be utilized in food science for flavor or nutritional research, though its industrial applications are less common.

2'-O-Methylguanosine (CAS: 2140-71-8) is generally considered safe when handled properly, but standard safety precautions apply. It is low in acute toxicity, though prolonged exposure may pose risks. Users should wear gloves, safety goggles, and ensure adequate ventilation. Safety data sheets (SDS) recommend avoiding ingestion and skin contact, and compliance with OSHA and EPA guidelines is essential for safe handling.

2'-O-Methylguanosine (CAS: 2140-71-8) should be stored in a cool, dry place, preferably at 2-8°C, in airtight containers to prevent moisture absorption. Protection from light is crucial to maintain stability, and it should be kept away from heat sources. Storage in a desiccator or sealed plastic/glass containers is recommended to ensure long-term integrity and prevent degradation.