2-Methyl-2-propanyl [(1S)-1-(5-fluoro-4-oxo-3-phenyl-3,4-dihydro-2-quinazolinyl)propyl]carbamate(CAS: 870281-85-9)

This compound is a crystalline solid with a molecular weight of approximately 511.53 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and dichloromethane. Chemically, it is reactive towards nucleophiles and displays good stability under acidic conditions. It exhibits moderate hydrolytic stability in neutral and basic media.

This compound is typically synthesized via a multistep process involving amidation and cyclization reactions. The key steps include the formation of an intermediate amide through reaction of a carboxylic acid with a primary amine, followed by the cyclization of the intermediate to form the quinazoline ring. The synthesis is achieved with high selectivity and moderate to good yield.

This compound is primarily used in the pharmaceutical industry for the development of new drug candidates. It may also find applications in the production of chemical sensors and semiconductors due to its specific reactivity and molecular structure.

Proper personal protective equipment (PPE) is essential when handling this compound. Wear gloves, goggles, and a laboratory coat. Store the compound in a cool, dry place away from direct sunlight. In case of a spill, clean up with care using appropriate absorbent materials and ensure proper disposal. Always consult the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.