(R)-1-(4-Methoxyphenyl)ethanol(CAS: 1517-70-0)

(R)-1-(4-Methoxyphenyl)ethanol is a colorless to pale yellow liquid with a molecular weight of 168.18 g/mol and a density of 1.03 g/cm³. It has a characteristic odor and is slightly soluble in water but miscible with organic solvents. It is relatively stable but can react with strong acids and bases. It is used in various applications due to its reactivity and functional groups.

(R)-1-(4-Methoxyphenyl)ethanol can be synthesized via a chiral auxiliary approach, utilizing a chiral resolving agent or via asymmetric reduction of a suitable precursor. Common methods involve the use of organocatalysts or metal complexes, providing high enantiomeric excess with good yield. Protective group strategies are also employed to control the reactivity of the substrate.

(R)-1-(4-Methoxyphenyl)ethanol is widely used in the pharmaceutical industry for the synthesis of chiral drugs, in the production of polymers for medical devices, and in the manufacturing of sensors and semiconductors. Its ability to form chiral molecules makes it valuable in these sectors.

When handling (R)-1-(4-Methoxyphenyl)ethanol, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up with appropriate absorbent materials, and disposal should follow local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.