4-(5-Methyl-1,2,4-oxadiazol-3-yl)benzoic acid(CAS: 95124-68-8)

4-(5-Methyl-1,2,4-oxadiazol-3-yl)benzoic acid (CAS: 95124-68-8) is a white crystalline solid with a high molecular weight of approximately 232.22 g/mol. It has a low solubility in water but is soluble in common organic solvents like ethanol and acetone. Chemically, it is a weak acid and exhibits moderate reactivity with bases and nucleophiles. It is stable under normal conditions but should be stored away from moisture and heat.

4-(5-Methyl-1,2,4-oxadiazol-3-yl)benzoic acid (CAS: 95124-68-8) can be synthesized via the condensation of 4-benzoic acid with methyl isothiocyanate followed by the reaction with sodium hydride to form the oxadiazole ring. This method provides good yield and selectivity, making it a common approach in the synthesis of this compound.

4-(5-Methyl-1,2,4-oxadiazol-3-yl)benzoic acid (CAS: 95124-68-8) is primarily used in pharmaceuticals due to its potential as a drug intermediate. It also finds applications in the synthesis of polymers, sensors, and semiconductors, contributing to advancements in material science and electronics.

When handling 4-(5-Methyl-1,2,4-oxadiazol-3-yl)benzoic acid (CAS: 95124-68-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood to avoid inhalation of dust. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.