Chondroitin, 4-(hydrogen sulfate)(CAS: 24967-93-9)

Chondroitin, 4-(hydrogen sulfate) is a crystalline compound with a molecular weight of approximately 422.11 g/mol. Its solubility in water is moderate, and it is slightly soluble in ethanol. This compound is known for its reactivity with bases and nucleophiles. It can form salts and esters, and its chemical stability is moderate under normal conditions.

Chondroitin, 4-(hydrogen sulfate) is typically synthesized through the sulfation of chondroitin sulfate, a process that involves treating chondroitin with sulfur trioxide in pyridine or other suitable solvents. The reaction is catalyzed by sulfur trioxide and has good selectivity for the 4-position of the glycosaminoglycan chain. The overall yield is moderate, around 70-80%.

Chondroitin, 4-(hydrogen sulfate) is primarily used in the pharmaceutical industry for the formulation of drugs and supplements. It is also utilized in the polymer industry for the production of biodegradable polymers. Additionally, it has applications in the sensor and semiconductor industries due to its chemical and biological properties.

When handling Chondroitin, 4-(hydrogen sulfate), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and fire sources. In case of a spill, it should be contained and cleaned up using appropriate procedures. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.