5-Methyl-3(2H)-pyridazinone(CAS: 54709-94-3)

5-Methyl-3(2H)-pyridazinone (CAS: 54709-94-3) is a crystalline solid with a molecular weight of approximately 121.12 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. The compound exhibits good stability under neutral and slightly acidic conditions but is susceptible to hydrolysis in strongly acidic or basic media. It is not highly reactive under normal laboratory conditions.

5-Methyl-3(2H)-pyridazinone can be synthesized through the reaction of methyl isonicotinate with sodium hydroxide to form 5-methylpicolinic acid, which is then heated to form the pyridazinone. Alternatively, it can be prepared by the condensation of 2-methylisonicotinic acid with hydrazine hydrate. The reaction is typically performed under mild conditions to ensure high yield and selectivity.

5-Methyl-3(2H)-pyridazinone (CAS: 54709-94-3) is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also finds applications in the sensor industry due to its specific chemical reactivity and in the semiconductor industry for its use in certain photoresists and patterning processes.

When handling 5-Methyl-3(2H)-pyridazinone (CAS: 54709-94-3), it is essential to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or under a fume hood. Spills should be contained and cleaned up using appropriate absorbent materials. For detailed safety information, refer to the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS).