(R)-Methyl 3-hydroxytetradecanoate(CAS: 76062-97-0)

(R)-Methyl 3-hydroxytetradecanoate is a white crystalline solid with a molecular weight of approximately 236.34 g/mol. It is slightly soluble in water and has a high solubility in organic solvents such as ethanol and acetone. Chemically, it is reactive towards nucleophiles and can undergo esterification and hydrolysis reactions. It is stable under normal storage conditions but should be protected from strong acids and bases.

(R)-Methyl 3-hydroxytetradecanoate can be synthesized via a Wittig reaction or by the hydrolysis of methyl 3-hydroxytetradecanoic acid. Commonly, a Wittig reagent is generated from tetradecanoyl chloride and phenyl phosphorane, which then reacts with methyl alcohol to form the desired ester. The reaction is typically carried out in an organic solvent under basic conditions to improve yield and selectivity.

(R)-Methyl 3-hydroxytetradecanoate is used in the pharmaceutical industry as a precursor for certain drug synthesis. It is also utilized in the polymer industry for the development of biodegradable polymers. Additionally, it can be employed in the production of biosensors and in the formulation of cosmetic products due to its hydroxy functionality.

When handling (R)-Methyl 3-hydroxytetradecanoate, appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risk. Spills should be immediately cleaned up with appropriate absorbents, and the area should be flushed with water. Safety data sheets (SDS) should be consulted for detailed handling and disposal information.