(2S)-2-(Benzylamino)-1-propanol(CAS: 6940-80-3)

(2S)-2-(Benzylamino)-1-propanol is a colorless liquid with a molecular weight of approximately 174.25 g/mol. It is slightly soluble in water but more soluble in organic solvents. This compound is known for its reactivity, particularly in nucleophilic substitution reactions. Its crystalline form is also known, although less common due to its liquid nature at room temperature.

(2S)-2-(Benzylamino)-1-propanol can be synthesized through a multistep process involving benzylamine and propanol. Commonly, a Grignard reagent of propanol is reacted with benzyl chloride to form the intermediate, which is then treated with aqueous sodium hydroxide to yield the final product. This process requires careful control of reaction conditions to achieve high yield and selectivity.

(2S)-2-(Benzylamino)-1-propanol finds applications in pharmaceuticals, where it serves as a precursor for drug synthesis. It is also used in the polymer industry for the modification of polymer properties. Additionally, this compound is utilized in the production of sensors and semiconductors, particularly in the development of organic electronic devices.

When handling (2S)-2-(Benzylamino)-1-propanol, it is crucial to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. In case of a spill, immediately clean up using appropriate absorbent materials and follow local safety guidelines. Always consult the Material Safety Data Sheet (MSDS/SDS) for detailed handling instructions.