5-Ethyldihydro-2(3H)-furanone(CAS: 695-06-7)

5-Ethyldihydro-2(3H)-furanone is a colorless to pale yellow liquid with a molecular weight of approximately 122.16 g/mol. It has a bitter taste and is poorly soluble in water but soluble in organic solvents. It is moderately reactive with ketone-like properties and can undergo dehydration and rearrangement reactions.

5-Ethyldihydro-2(3H)-furanone can be synthesized via the amidolysis of ethyl furan-2(3H)-carboxylate with sodium hydroxide. The reaction typically yields a 70-80% yield with high selectivity for the desired product. This method involves the formation of an intermediate amidine followed by hydrolysis to the final furanone.

5-Ethyldihydro-2(3H)-furanone is primarily used in the flavor and fragrance industry, providing a sweet, caramel-like aroma. It also has applications in the pharmaceutical industry for synthesizing certain drugs. Additionally, it is used in the polymer industry as a stabilizer and in the sensor industry for its reactive properties.

When handling 5-Ethyldihydro-2(3H)-furanone, always wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Ensure the use of a fume hood for any operations involving the compound. Spills should be immediately cleaned up with appropriate absorbents, and the area should be well-ventilated. Refer to the safety data sheet (SDS) for detailed safety instructions and emergency procedures.