5-Bromo-4-chlorothieno[2,3-d]pyrimidine(CAS: 814918-95-1)

5-Bromo-4-chlorothieno[2,3-d]pyrimidine is a solid and crystalline compound with a molecular weight of approximately 248.01 g/mol. It has a solubility of 0.1 g/100 mL in water and is slightly soluble in common organic solvents such as ethanol and acetone. This compound is known for its low reactivity under normal conditions but can undergo substitution reactions under certain conditions. It is stable under normal temperature and pressure but should be stored in a cool, dark place to prevent degradation.

5-Bromo-4-chlorothieno[2,3-d]pyrimidine is typically synthesized through a multi-step chemical process involving the bromination and chlorination of thieno[2,3-d]pyrimidine. Commonly, this involves reacting thieno[2,3-d]pyrimidine with bromine and chlorine in the presence of a suitable solvent and catalyst. The yield is around 70-80% with good selectivity and purity.

5-Bromo-4-chlorothieno[2,3-d]pyrimidine is primarily used in the pharmaceutical industry for the development of new drugs, particularly in the area of antiviral and anti-inflammatory agents. It is also used in the chemical industry for the synthesis of other compounds and in the electronic industry for its use in semiconductors and sensors.

When handling 5-Bromo-4-chlorothieno[2,3-d]pyrimidine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves and safety glasses. It should be used in a well-ventilated area or a fume hood to prevent inhalation. In case of a spill, ensure to clean it up with caution and use appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.